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Figure 6 Tirapazamine (TPZ) is a novel anticancer drug that exerts its antitumour effect under hypoxic conditions (188)

Gut-mediated inter-organ axes Gutliver axis: a central hub of inter-organ crosstalk The gastrointestinal tract and the liver constitute two major metabolic organs in dairy cows and are functionally interconnected through a bidirectional gutliver axis mediated by multiple signaling molecules

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Arachidonic acid is oxidized into different molecules that are called eicosanoids and includes molecules such as prostaglandins and thromboxanes

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