Treatment of these cells with lapatinib, statins, trigonelline, or through genetic editing to suppress GPX4 expression can induce ferroptosis and reverse their tumor-promoting functions [28, 58, 88]
The approach to treatment is typically conservative at first, including non-surgical interventions like wrist splinting, avoidance of activities that might exacerbate the condition, and nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief
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In ESCC, lncRNA AP001885.4 is upregulated and predicts unfavorable outcomes
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