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Over the past 30 years, several interventions and numerous preclinical studies have been shown to slow aging and increase the healthy lifespan of organisms from yeast, flies, rodents to non-human primates

Furthermore, advancements in delivery systems and the development of standardized formulations are crucial for enhancing the bioavailability and therapeutic effectiveness of PCs

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In a third phase, the analysis of the culture cells was carried out to determine the accumulated intracellular iron in the untreated and treated cultures and the effectiveness of the tested compound for the reduction or reversal of the intracellular iron accumulation was determined by Prussian Blue staining and brightfield microscopy [19]