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In particular, pretreatment with the GHSR1a inverse agonist SP-analog results in cross-sensitization to the 5-HT 2C response in cells coexpressing GHSR1a and 5-HT 2C (Schellekens et al., 2013)

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We recruited BP patients that exhibited at least one psychotic episode because they share some of the neurocognitive or neuroanatomical deficits observed in SZ