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In comparison with non-smokers, the smokers showed smaller GM volume in the left dorsal medial thalamus

"The problematic and the perplexing aspect of regulation, of course, is the individual versus the population level," says Geoffrey Fong, principal investigator at the International Tobacco Control Policy Evaluation Project at the University of Waterloo

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Chronic cannabis smoke inhalation in animal models leads to recruitment of immune cells to the lungs, including macrophages [139]