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[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Aggarwal R., Vaduganathan M., Chiu N., Bhatt D.L

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[98] There are also a number of drugs where the anti-folate effect is unintended

Quercetin exhibits anti-inflammatory properties by inhibiting inflammatory signaling pathways, including PKC-JNK1/2-c-Jun and NF-B, decreasing the synthesis of inflammatory mediators, including TNF-, and suppressing the expression and activity of intercellular adhesion molecule-1 (ICAM-1) and matrix metalloproteinase-9 (MMP-9), thus mitigating the recruitment and dissemination of inflammatory cells ( The chemical structural similarity between kaempferol and quercetin endows them with similar biological characteristics and functions