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ROS profoundly influence transcriptional reprogramming by modulating the activity and expression of several transcription factor (TF) families, including WRKY, Zat, RAV, GRAS, and MYB ( 2 O 2 have revealed the presence of H 2 O 2 -responsive cis-regulatory elements within promoters of oxidative stressinduced genes, underscoring the existence of a redox-sensitive transcriptional network ( 2 accumulation, highlighting their role as positive and negative regulators of ROS signaling ( Recent studies reveal that various cellular mechanisms produce ROS, whereas the antioxidant system is complex and multifunctional

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Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection