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Moreover, scars can progress pathologically into hypertrophic scars and keloids characterized by uncontrolled fibroproliferation, the continuous accumulation of ECM and cells, and, in the case of keloids, invasion of adjacent healthy skin [150, 153, 154]

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In rodents post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) could significantly reduce infarct volume and neurological deficits, but the optimal dosage and timing remain elusive

46 The cysteine protease family, caspases, orchestrate apoptotic cell death