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Several features enabled us to distinguish severe from moderate IPTB, for instance higher levels of total sulfur amino acids (AAs) ( P 0.05), and total glutathione-precursors ( P 0.03), as well as levels of individual methionine ( P 0.03), homocysteine ( P 0.002) (whereas the difference in cysteine was not significant, P 0.09), and serine ( P 0.04) in maternal blood at delivery, mainly in placebo arm

Depletion of GSH leads to exacerbation of damage by oxidative and nitrosative stress

Moreover, the route of estrogen administration significantly alters the effect of estradiol on GH release

The global population aged 60 and above will double to 2.1 billion by 2050, and the population aged 80 and above will reach 426 million