Excess iron can drive oxidative stress , essentially creating internal "rust", which damages cells, contributes to inflammation, and ironically impairs detoxification
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Figure 6 The association of sarcosine and serine with clinical manifestations in LC In our investigations of metabolite levels associated with symptoms commonly seen in LC patients such as cognitive function, anxiety, chronic pain, and depression in LC patients, we conducted additional analyses
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FIGURE 7 Persistent accumulation of ROS induces lipid peroxidation in keratinocyte membranes and structural proteins, resulting in impaired barrier function and increased TEWL (Yang et al., 2022
