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Medicines which can decrease the absorption of Vitamin B12 include: Colchicine (a medicine used to treat gout) Metformin (an anti-diabetic agent) Excessive Alcohol Vitamin C products

Sources: Institute of Medicine, Food and Nutrition Board, National Academies of Science, Dietary Reference Intakes (DRI): Recommended Dietary Allowances and Adequate Intakes , USA 2018, Mustafa Vakur Bor, Kristina M von Castel-Roberts, Gail PA Kauwell, Sally P Stabler, Robert H Allen, David R Maneval, Lynn B Bailey Ebba Nexo Daily intake of 4 to 7 g dietary vitamin B-12 is associated with steady concentrations of vitamin B-12related biomarkers in a healthy young population Am J Clin Nutr 2010 91: 3 571-577

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The bacteria responded by producing compounds called porphyrins, LiveScience reported, which are known to promote the kind of inflammation that previous research has linked to the appearance of severe acne