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It takes the awkwardness out of saying no to a cigarette by printing the plea right on the fabric

Choose life, ditch the pipe

In vitro experiments have shown that tobacco smoke extract activates the MAPK/AP-1 signaling pathway and promotes aberrant proliferation of urothelial cells 23 , while nicotine contributes to tumor progression and chemoresistance through activation of the PI3K/AKT/mTOR signaling axis 24

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In summary, the estimated change in the smoking prevalence obtained from this study is comparable to the results of other studies, though the sampling design and time of the survey may be different