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Erythema multiforme minor, a polymorphous maculopapular lesion, spreads peripherally and clears centrally to form an annular pattern, which is called a target lesion

Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, et al

Introduction Abiotic and biotic stresses are a regular feature in natural plant environment

J Thorac Dis 12(5):1952-1959, 2020

But it will be recognized by the immune system in excess, activating the Toll-like receptor 4 (TLR 4) signaling pathway, and promoting the release of immune cells to release a large number of pro-inflammatory cytokines, such as TNF- and IL-6 (Qu et al., 2023)