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Meanwhile, DHA reduces the expression level of the COX-2 enzyme in cancer cells and decreases oncogenic inflammatory signaling mediated by COX-2 (54)

4 Challenges and perspectives of ferroptosis in kidney diseases Ferroptosis, an iron-dependent regulated cell death driven by lipid peroxidation, has emerged as a central pathogenic mediator in kidney diseasesan organ uniquely susceptible to redox imbalance due to its high metabolic activity, abundant iron handling, and structural heterogeneity (276, 277)

97 Furthermore, antioxidants derived from plants can be combined with nephrotoxic drugs like cisplatin, contrast media, and others

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Poole PJ, Black PN: Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review