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In addition, although the design is pragmatic to include those with psychiatric or substance use comorbidities, trial burden (weekly visits, adherence to the protocol) might make retention problematic for these participants

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You will actually have the best experience by customizing how you use the tincture depending on: Your own personal experience with different tincture doses Why you are taking the cannabis tincture Whether you are taking a CBD or THC tincture The general rule is to start out with a low dose and adjust as needed to achieve the desired effects

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Filter ventilation is moderate, and tobacco packing is neither overly loose nor tightly compacted