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Data from the 16th Korean Adolescent Health Behavior Survey conducted in 2020 revealed that the rate of secondhand smoke exposure in adolescent families was 20.0% for boys and 22.4% for girls, surpassing rates observed in other countries 16,17

Further oxidation of Hz and AcHz by CYP450 enzymes, particularly CYP2E1, generates reactive intermediates that form covalent adducts with endogenous macromolecules, a process implicated in INH-induced hepatotoxicity (Yue et al., 2004