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5.3 Regulatory and consumer acceptance challenges Hand-in-hand with safety concerns are the regulatory and public acceptance challenges for nanoencapsulated nutraceuticals

Amino acids as central neurotransmitters

Tomson et al., 2023), as shown in Figure 1B

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Senescent microglia may have a reduced capacity to modulate neuronal activity because of genetic changes that result in reduced surveillance, migration, and sensitivity to endogenous ligands, and a heightened sensitivity to pathogens, as seen in 24-month-old mice (Hickman et al., 2013