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Unlike existing TKIs, IDRX-42 is designed to target a broader range of clinically relevant primary and secondary KIT mutations, addressing a key limitation in current treatment options

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However, they also agree: stopping smoking and seeking targeted treatments can deliver real, visible improvements

People with abnormal liver function or a history of liver disease, diabetes, active peptic ulcer disease, gout, cardiac arrhythmias, inflammatory bowel disease, migraine headaches, or alcoholism may be more susceptible to the adverse effects of excess niacin intake than the general population (41)