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Exposure to EC aerosols enhanced susceptibility to infection, as shown by increased inflammatory responses in Porphyromonas gingivalis- and Fusobacterium nucleatum- challenged epithelial and malignant cell lines, highlighting a dysbiotic microbiome and immune dysregulation in EC users [61]

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When introduced in other countries, pictorial cigarette warnings have been shown to increase understanding of the negative health consequences of smoking (Refs