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Smoking is associated with an increased risk of dementia: A meta-analysis of prospective cohort studies with investigation of potential effect modifiers

51 Upon the knockout of PINK1 or PRKN, exhaustive exercise and mutational stress of mtDNA activated the DNA-sensing cGAS-STING pathway and led to an inflammatory phenotype

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Studies have shown that administration of nicotine in rats causes an increase in Basal layer collagen fibers, destruction of Sertoli cell intercellular connections, chromosomal abnormalities, degenerative germ cells, excessive accumulation of fat droplets in the sperm cytoplasm, and morphological abnormalities in the sperm [37]