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How smoking leads us to cancer is by damaging our DNA, including some key genes that give us protection against the cancer

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When the smoker takes the first puff off of that cigarette, the nicotine hits their brain within seconds

See our E-cigarettes, vaping and the law factsheet for more information Evidence Base This factsheet was developed following expert review by researchers at the Matilda Centre for Research in Mental Health and Substance Use and Associate Professor Becky Freeman from the School of Public Health at the University of Sydney.