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Marieh Honarmand, Alireza Nakhaee, and Mohammad Moradi, Comparison of Salivary Cotinine Concentrations in Male Smokers and Smokeless Tobacco Users, 2018

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They discovered that men who smoked just one cigarette were 74 percent more likely to develop coronary heart disease than nonsmokers were, even when the researchers adjusted for possible factors that could skew the results, like age and other heart risks like high cholesterol

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The comparison of THC vs Cannabis highlights an important distinction: THC is a single compound, while cannabis refers to the entire plant containing various cannabinoids, including CBD and THC