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In hepatocytes, ATP7A and ATP7B are located mainly in the trans-Golgi network and supply copper for incorporation into copper-dependent enzymes such as tyrosinase, peptidylglycine amidating monooxygenase, dopamine monooxygenase, lysyl oxidase, and ceruloplasmin [205]

The experiment was carried out in three biological replicates on different days with cells from different passages

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