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In addition, microglial reactivity occurs later and is weaker in the gray matter, resulting in lower levels of cytokine production (Gudi et al., 2020)

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Unlike native amylin, which is rapidly degraded, Cagrilintides structural modifications allow for once-weekly subcutaneous administration, improving clinical practicality and adherence

[DOI] [PubMed] [Google Scholar] 270.Lugg J.A., Rajfer J., Gonzlez-Cadavid N.F

Metabolic Effects and Hypoglycemia Risk As an insulin-like peptide, IGF-1 DES can lower blood glucose through enhanced glucose uptake, insulin-mimetic effects, improved insulin sensitivity, but risk of hypoglycemia at high doses