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The absence of a drug affinity complex (DAC) yields a shorter functional half-life in experimental models (approximately 30 minutes to two hours [1]) allowing researchers to examine time-dependent signaling dynamics and pulsatile secretion patterns that more closely mirror endogenous GHRH activity

International Journal of Molecular Sciences 25(14)

However, since it mimics ghrelin (the hunger hormone), some users may notice a slight increase in appetite when they first start using it

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