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The genesis of ROS, in most cases which is H 2 O 2 , is carried out by various peroxisomal enzymes, for example, the degradation of fatty acid during the participation of acyl-CoA oxidase in the -oxidation pathway

The average MMGBSA binding energy was observed to be lower (better) in case of the Juglone-C3-Glutathione adduct (-55.07 kcal/mol) (Figure 9 B) than that of Juglone-C2-Glutathione adduct (-47.76 kcal/mol) (Video S3)

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Research indicates Dihexa treatment can improve functional outcomes in animal models of cognitive impairment, with behavioral improvements correlating with structural brain changes including increased synaptic density and improved neural connectivity patterns