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Many successful outcomes involve gradual rather than dramatic initial changes

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Nausea usually eases with time at a held dose, while persistent constipation often requires separate management

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(7) Solid tumors, inflammatory, and autoimmune states Marked or persistent unexplained elevation has been linked to malignancy in observational data

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So why hasnt the research caught up

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Trends in Molecular Medicine, 11(9), 421-429

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