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As the primary redox buffer, it regulates the ratio between its oxidized form (GSSG) and reduced form (GSH), which determines the entire cellular redox environment

Disulfiram, in combination with copper, has emerged as a potent inducer of ferroptosis across various cancer types, including triple-negative breast cancer, renal cell carcinoma, hepatocellular carcinoma, nasopharyngeal cancer, oral squamous cell carcinoma, and non-small cell lung cancer

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The potential role of platelets in the consensus molecular subtypes of colorectal cancer