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Gerard points out its similarity to henbane, in that it "bringeth drowsinesse, troubleth the sences, and maketh a man as it were drunke by taking the fume only." That sedating effect led to its signifying "contentment" or "I soothe you" in the Victorian Language of Flowers

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When someone inhales nicotine, chemicals are released in the brain that quickly attaching to the various receptors