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Given the biphasic dose-response curve described above for cardiovascular effects, a reconstitution error that doubles the intended dose may shift the patient from a vasodilatory to a vasopressor pharmacodynamic regime

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Liu, Y., et al., Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway

Bridging these gaps is essential for transforming descriptive knowledge into predictive and translational frameworks