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Both NF-B signaling and mtROS promote NLPR3 inflammasome assembly, a key driver of neuroinflammation that leads to cleavage of precursor cytokines into biologically active pro-inflammatory cytokines, IL-1 and IL-18 (Blevins et al., 2022)

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After 10 minutes, they became sleepy, with a tottering walk, repeatedly falling down while after 20 min they started to exhibit jerking of the extremities

Graphical abstract Various mechanism of action of anticancer peptides