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We were able to reach a significantly higher number of identified phosphopeptides using pS-MIP compared to TiO 2 enrichment with a modest but reproducible phosphopeptide recovery of up to 40%

First, we investigated whether TfR1 levels were altered with RSL3 in PTC cells, as TfR1 has been shown to be a better marker of ferroptosis 22

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The exacerbation of endothelial dysfunction and vascular injury in the presence of elevated uric acid levels suggests a critical need to understand the underlying molecular mechanisms