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The key is to treat optimization like an experiment measure, adjust, and let your physiology guide the protocol changes (if any)

Returning to the definition of half-life as the time required for the blood level to drop by half, if the steady state blood level of a drug with linear pharmacokinetics is considered to be 100%, then, if the drug is suddenly withdrawn, its level will drop to 50% after the first half-life, to 25% after the second half-life, to 12.5% after the third half-life, to 6.25% after the fourth half-life, and to 3.125% after the fifth half-life (Figure 1)

Kwak et al., 2020)

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The frequency of glutathione IV therapy can vary depending on individual health conditions and the desired outcomes