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Description

The failure of these treatments to restore function and slow functional disease progression can be traced to their inability to correct the underlying cause of the dysfunction- diminished synaptic connectivity among neurons in the striatum and neuronal loss in the substantia nigra (SN)

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An alternative approach is the use of inhibitors of DPP IV, such as sitagliptin, P32/98 (H-Ile-thiazolidide hemifumarate), NVP DPP 728 (N-[2-(5-Cyanopyridin-2-ylamino) ethyl]-Gly-Pro-nitrile) and the Gly- Pro-nitrile-derived compounds vildagliptin and saxagliptin

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As usual, WADA also made clarifications to the List to help athletes and their support teams better identify and understand prohibited substances and methods

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Most vials have a rubber stopper secured by an aluminum crimp seal

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