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2 Diuretics: brief historic perspectives 2.1 Thiazides and thiazide-like diuretics Hydrochlorothiazide and chlorthalidone, a benzothiadiazide and a thiazide-like diuretic, respectively were introduced during 1957-59 and the former quickly became a mainstay in the treatment of hypertension

The gut microbiota in MS varies with disease activity, with specific bacterial populations correlating with relapse status and lesion formation

Vitamin B12 deficiency when pregnant may increase the risk of premature delivery

Cardiovascular side effects, while less common, may include changes in heart rate, with some patients experiencing a mild increase in resting heart rate of two to three beats per minute on average

Glutathione is a short peptide (Glu-Cys-Gly) that displays a high affinity toward glutathione S-transferase (GST)