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Although electronic cigarettes (e-cigarettes) are not an FDA approved nicotine replacement therapy (NRT), switching from combustible tobacco products to e-cigarettes may be considered a useful alternative for smokers with COPD, but more evidence is required to establish potential harm reduction

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[15] Nicotine is typically consumed through tobacco smoking, vaping, or other nicotine delivery systems

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10.1164/rccm.201908-1683LE [DOI] [PMC free article] [PubMed] [Google Scholar] 47.Stoller JK, Aboussouan LS