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The resulting peptide has a nearly identical 3D spatial arrangement of functional groups as the originalmaintaining target binding affinitybut is unrecognizable to proteases that cleave L-amino acid peptide bonds

The review also discusses the challenges in targeting 7nAChR and its implications for medication development and prospective avenues for further investigation

Despite advances in the understanding of its clinical features, effective treatments remain elusive, necessitating further exploration of the underlying mechanisms and novel therapeutic targets

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Gastroenterology 154 , 13091319.e7 (2018)