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Cigarette smoke extract (CSE) was prepared fresh (used within 1 hr) from filter-less research-grade cigarettes (3R4F, Tobacco Research Institute, University of Kentucky, Lexington, KY) as described previously [5]

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that the authors did not have health data measuring participants baseline lipid profile or blood pressure

At age 16, we saw that almost 60 percent had used cigarettes more than 20 days in the past year and by 18, every single kid in this group reported heavy use of cigarettes. A statistical analysis showed that adolescents who experienced early childhood physical abuse were 2.3 times more likely to be in the sharply increasing cigarette use group compared with the stable no/low group