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Management of smoking in pregnant women

Boxplots and heatmaps were constructed using the ggplot2 113 and RColorBrewer (colorbrewer2.org) packages conducted in R version 3.1.2 114

The study found that nearly all e-cigarettes sold contained nicotine, with the average nicotine concentration in e-cigarette products increasing from 2.10% to 4.34% between 2013 and 2018, a 106.7% increase

Nicotine stimulates the adrenal medulla to release adrenaline, and directly stimulates the sympathetic nervous system, resulting in increased heart rate, blood pressure, peripheral vascular resistance and myocardial contractility

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