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Study author Ludmil Alexandrov said in a statement that before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking. Co-author Sir Mike Stratton added that looking in the DNA of cancers can provide provocative new clues to how cancers develop and thus, potentially, how they can be prevented.

30 CuiJ.WuF.YangX.LiuT.XiaX.ChangX.et al (2020)