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In the following years, the design of the THS 2.2 was further refined for large-scale manufacturing and to make the device lighter and easier to hold

Reynolds has long recognized the potential appeal of such products to youth, noting in one internal document that the ideal youth cigarette should include 'some useful, demonstrable novelty in filter, mouthpiece, package or other aspect of the product system.'" They claim that a large portion of the readership of these magazines at least 12.9 million consists of teenagers between the ages of 12 and 17

Int J Mol Sci 2023, 24