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Extracts from tobacco rods were serially diluted and superfused over HEK293T cells expressing the human TRPM8 cold/menthol receptor activated by menthol, WS-3 and other synthetic cooling agents, measuring activity by Calcium-microfluorimetry as published (Supplementary file) 3

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Maintenance Tips for Your Powermatic V+ To keep your Powermatic V+ performing optimally, follow these maintenance tips: Regular Cleaning : Remove excess tobacco and residue from the machine after each use to prevent clogging