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4 While timely recognition and intervention are crucial for mitigating the adverse effects of APAP overdose, effective treatment options are available to manage hepatotoxicity and prevent progression to liver failure

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We have confirmed that these TYR-catalyzed in-situ formed PRTOACs could effectively degrade overexpressed TYR in the melanocytes and subsequently decrease the melanin levels for alleviating skin hyperpigmentation within 48 h on a mouse model

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