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For this population-based research, investigators pooled data from large cohort studies conducted in Asia and included demographic and risk factor information collected in seven Asian regions from the early 1960s through the late 1990s (although most of the studies enrolled participants after the mid-1980s)

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Importantly, COPD primary bronchial epithelial cells (PBECs) displayed similar changes in mitochondrial morphology as observed in long-term CSE-exposure BEAS-2B cells

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