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The oral microbiome, first observed by Antonie van Leeuwenhoek in 1670 using his self-designed microscope, is the second-most diverse microbiome after the gut microbiome

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37,38 The active components in e-cigarettes are not regulated by the extraction process, and their suspension in e-liquid varies greatly

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The study noted that former smokers also had an increased risk of heart disease even 20 years after quitting