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Purinergic Signaling in Acute Pulmonary Inflammation Extracellular nucleotides and nucleosides (particularly ATP and adenosine) along with the ectonucleotidases CD73 and CD39 (responsible for the conversion of ATP to adenosine) and nucleoside transporters (ENTs) have been demonstrated to play essential roles in the pathogenesis of acute pulmonary inflammation (Figure 3)

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