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As of this writing, Washington, D.C., and 24 states see recreational marijuana (which includes vaping) fully legalized and decriminalized: Alaska, Arizona, California, Colorado, Connecticut, Delaware, Illinois, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nevada, New Jersey, New Mexico, New York, Ohio, Oregon, Rhode Island, Vermont, Virginia and Washington

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Furthermore, tobacco smoke induced lower airway dysbiosis in COPD, enriching oral commensals and promoting inflammatory pathways involving IL-17, IL-6, ERK/MAPK, and PI3K