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[61] Chronic nicotinic acetylcholine receptor activation from repeated nicotine exposure can induce strong effects on the brain, including changes in the brain's physiology, that result from the stimulation of regions of the brain associated with reward, pleasure, and anxiety

W., Crippa, J

Tobacco product advertising and promotions : In 2019, nearly 9 in 10 middle and high school students (22.9 million) reported exposure to tobacco product advertisements or promotions from at least one source

Theres just that extra bit of risk

Avoid moving the pouch around too much to prevent irritation and ensure a consistent release of nicotine