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This is much lower than would be expected to occur naturally in a general population of this size and is similar across other licensed COVID-19 vaccines." March 18: The European Medicines Agency (EMA) issued a statement that the benefits of the AstraZeneca vaccine outweigh the risks

However, the large proportion of CFTR expression deriving from other epithelial cell types and our observation of FOXI1 / CFTR decoupling by time course and knockout electrophysiology cautions against the simple model where cystic fibrosis is caused by loss of CFTR function in FOXI1 + ionocytes