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In the early 1960s, roughly 40 percent of adult Americans smoked

COPD patients often experience pulmonary arterial constriction and spasms due to restricted airflow and chronic hypoxia, leading to pulmonary hypertension, a common COPD complication 28,29

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Relationship to Netsuke, Ojime, and Kiseru-zutsu A defining characteristic of the tabako-ire is its integration into a complete smoking ensemble